Searching For Anti-Anxiety Strains
Hoping to find a blend of cannabinoids and terpenes (called a “chemotype”) that can effectively treat anxiety, researchers on this study first looked at whether particular strains were associated with reduced anxiety.
“Patients report having distinct preferences for certain strains over others and little research has been done on what, if anything is different between strains they like or dislike for a condition” explained Daniel Lantela, co-founder and drug development director at Whistler Therapeutics.
“By asking patients which strains they liked or disliked, we could correlate their choices to the chemotype.”
To gather this information, researchers worked exclusively through one dispensary, surveying 442 of their patients about the specific strains sold there and reviewing two sets of independent lab tests on the strains’ chemical composition.
Respondents were asked to rate the most and least effective strains (from a list of the dispensary’s 25 most commonly sold options), and used a one to ten scale to rate how effective those strains were at reducing their anxiety.
Whistler Therapeutics’ four highest-rated strains for relieving anxiety were:
Whistler Therapeutics’ four worst-rated strains for relieving anxiety were:
The Chemical Fingerprints of Chill
Next, researchers turned to analyzing the lab results for patterns amongst the most and least effective strains.
The analysis revealed a pattern of high THC and the terpene trans-nerolidol in the most effective strains. Three of the four were Kush varieties which all share a similar chemotype with high levels of trans-nerolidol, b-Caryophyllene, and D-limonene, and contain genetics from landrace strains found in the Kush mountain range in Central Asia.
Trans-nerolidol is found in many strong aromatics like jasmine, tea tree, and lemongrass. It delivers a subdued and nuanced floral aroma with notes of fruity citrus, apples, and